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KMID : 0882420120820030378
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Korean Journal of Medicine
2012 Volume.82 No. 3 p.378 ~ p.381
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A Case of Mycobacterium Marinum Tenosynovitis Diagnosed by the PCR-restriction Fragment Length Polymorphism of the rpoB Gene
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Jeong Ho-Jung
Lee Mi-Rae
Bae Sun-Youn
Kim Mi-Yeon
Chung Doo-Ryeon
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Abstract
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Mycobacterium marinum is an uncommon cause of skin and soft-tissue infection. The diagnosis of M. marinum infection is often delayed when only a conventional tissue culture method is used. PCR-restriction fragment length polymorphism (RFLP) analysis using the novel region of the rpoB gene is now available for the rapid identification of Mycobacteria. We report a case of hand infection caused by M. marinum that was identified by PCR-RFLP analysis. The PCR-RFLP assay is a specific and rapid method for the identification of Mycobacteria that facilitates the early diagnosis of non-tuberculous Mycobacterium infection.
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KEYWORD
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Mycobacterium marinum, PCR-restriction fragment length polymorphism (RFLP) analysis, rpoB gene
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